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The reasons for a link between vitamin B 12 deficiency and depression are not clear but may involve a shortage in S-adenosylmethionine (SAM)

Biomedicines 10 (12), 3088

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Zincs ability to reduce inflammation and enhance immune response makes it a promising agent for mitigating these chronic diseases, which are prevalent in aging populations and often worsen with immune decline

According to previous investigations, APO ameliorated lung damage by reducing lipid peroxidation, inhibiting NOX expression and activity, blocking the NF-B pathway, and suppressing the transcription of pro-inflammatory cytokines in lung tissue (Kim et al