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A study employing high-resolution immunocytochemistry at both light and electron microscopic levels in rodents has demonstrated that neurons efficiently uptake lactate via monocarboxylate transporter 2 (MCT2), a high-affinity transporter localized at postsynaptic densities to facilitate lactate import from astrocyte-released sources (Bergersen, 2007) and subsequently convert it to pyruvate via lactate dehydrogenase isotype 1

L.CammannD.PowellJ.ChenJ

Finally, in the context of an adult demyelination model, leucovorin and dyclonine also improve lesion repair by promoting in parallel a microglia-mediated myelin debris clearance, and a faster transition from pro-inflammatory to pro-regenerative microglial profiles

In November 2010, the AKC board warned the Dalmatian parent club that if its membership did not vote to approve admission of the LUA Dals into the AKC within the following six months, then AKC would take the matter into its own hands and rule on admitting the LUA dogs into the breed's studbook

Sanada, F