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Research published in studies examining synaptic density following Dihexa administration found elevated synaptophysin and PSD-95 expressionmarkers of presynaptic and postsynaptic densitysustained for 714 days after a single administration cycle

The 1mg arm was a fixed low-dose cohort with no escalation

As shown in the Figure above, at the end of a month, weekly nasal administration results in significantly higher serum Vitamin B12 levels than after intramuscular administration

Additionally, tumor-homing peptides have been conjugated with cargoes such as small-molecule or chemotherapeutic drugs via linkers to synthesize peptidedrug conjugates