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Furthermore, PXR-deficient lymphocytes produce more IFN-gamma and less of the anti-inflammatory cytokine IL-10 [9], which suggests that PXR suppresses Th1 inflammation

Aliquots for the majority of the blood-based measures were obtained from 8 ml heparin-anticoagulated WB (BD Vacutainer 4 ml Heparin Tubes) with the exception of samples for biochemistry (12 ml