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Single-cell RNA sequencing of liver tissue from two NASH patients showed that GPNMB was highly expressed in CD68-positive macrophages

doi: 10.1016/j.aquatox.2017.12.017 30 HouWYulinHWenlongYTianTPengFYuqiongDet al

SARS-CoV-2 affects intracellular GSH levels by decreasing intracellular NRF2 function, that plays a key role in protecting cells from oxidative damage by upregulating GSH production (Rahman and MacNee, 2000

Pre-clinical models of emphysema induced with oxidant stress and/or protease-dependent lung damage have also provided insights into the potential for antioxidants as therapies

It is identified clinically by the presence of jaundice, hepatitis, and systemic inflammatory response, which results in significant morbidity and mortality