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Under appropriate laboratory storage and handling, it may remain suitable for use for up to 28 days after the initial vial access

Currently there is some debate about whether the current B12 recommendations are sufficient to achieve optimum vitamin B12 status (Doets et al., 2013)

We note that in the CY 2020 PFS final rule (84 FR 62685) and CY 2021 PFS final rule (85 FR 84547), CMS indicated that TCM may be billed concurrently with other care management codes when relevant, medically necessary, and not duplicative