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The Hsieh et al

1,2 Even with a 12-fold increase of oral vitamin C from 200 mg/day to 2500 mg/day the plasma concentration of vitamin C only increases by 25% from 1.2 to 1.5 mg/dL and with further increased dosing only to 9.3 mg/ dL 1,2 .Similarly, oral supplementation with magnesium results in little or no change in serum magnesium concentrations, whereas IV administration can double or triple the serum levels at least for a short period of time

This may present as difficulty in breathing , lightheadedness , a rapid drop in blood pressure , or a feeling of tightness in the chest

Two types of skin infections are primary and secondary