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5 Natural flavonoids as ferroptosis inhibitors for the therapy of CNS diseases Flavonoids are one of the largest classes of plant polyphenols, characterized by a C6-C3-C6 backbone consisting of three rings labeled as A, B, and C (Dias et al., 2021)

10.1016/j.redox.2015.06.020 188 VermaA

In addition, E3 ligases anaphase-promoting complex subunit 2 (ANAPC2) promotes KRAS degradation through the ubiquitinproteasome pathway in colorectal cancer [179]