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10.1016/j.jconrel.2006.10.031 18 ChenJ.HuL.YangG.HuQ

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For some, there is the possibility that it will interact adversely with other injections or supplements that you are currently taking

A clear solution that has been properly stored within the stability window (21 to 30 days) should remain potent

If the Botox spreads into some of the muscles in the forehead, I always mention that there is a risk of eye lid droopiness (ptosis), although I have not seen this occur personally