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XL184 is useful at low concentration (0.10.5 M) to induce marked inhibition of constitutive and inducible c-Met phosphorylation and its consecutive downstream signaling in malignant peripheral nerve sheath tumor cells

Surprisingly, the current study has shown that plasma Hcy was not elevated but instead decreased in the first 2 weeks following pemetrexed therapy (Figure 4)

Moreover, patients in the HGSH group showed a higher incidence of postoperative recurrence and metastasis ( P = 0.003) (Table 3), as well as reduced DFS ( P = 0.001) and OS ( P = 0.026) (Fig

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