6.1 Marker gene sequencing for microbiome analysis Marker gene sequencing is a widely used and cost-effective approach in microbiome analysis that targets conserved genetic regions (e.g., 16S rRNA for bacteria and archaea, ITS for fungi, 18S rRNA for eukaryotes) to profile microbial community composition and diversity (Figure 3)
[Abstract]2024 Oct 27;16(10):1188-1198
Antioxidant levels in patients with autism showed decreased activity of glutathione peroxidise (GPx) in plasma and in erythrocytes, 62 reduced levels of total GSH, a lower redox ratio of reduced GSH to oxidized glutathione (GSSG) in plasma, 63 66 as well as decreased catalase and superoxide dismutase (SOD) activity in erythrocytes
We recently confirmed that enzymatically active Grx have two distinct glutathione-interaction sites, one glutathione-scaffold site that interacts with glutathionylated disulfide substrates (GSSR) during the oxidative half-reaction, and one glutathione-activator site that interacts with reduced glutathione (GSH) during the reductive half-reaction 7,11,12 (Fig
Dual faces of mitophagy in tumor initiation and progression Oncogenic KRAS mutation plays critical roles in the initiation and maintenance of PDAC progression and is associated with alterations in mitochondrial morphology and function
