glutathione cyclase Ascorbate Cycle Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost Glutathione in the Brain |

Disclosures: Dylan Windell: Perspectum: Employee, asd: Employee, Alastair Magness: Nothing to Disclose, Abhishek Roy: Nothing to Disclose, Paul Aljabar: Nothing to Disclose, Timothy Kendall: Nothing to Disclose, Eve Fryer: Nothing to Disclose, Kenneth Fleming: Nothing to Disclose, Rob Goldin: Nothing to Disclose, Caitlin Langford: Nothing to Disclose 776 THE USE OF AI-ASSISTED DIGITAL PATHOLOGY IN DETERMINING THE INFLAMMATORY BURDEN IN LIVER DISEASE Dylan Windell 1 Cayden Beyer 1 Sarah Larkin 1 Elizabeth Shumbayawonda 1 Paul Aljabar 1 Caitlin Langford 1 Andrea Dennis 1 Rob Goldin 2 , 1 Perspectum, 2 Imperial College London Background: Liver pathology assessment remains the reference standard for assessing disease activity despite well reported limitations, notably the high variability between readers especially in the assessment of inflammation

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Data are plotted as means with range of two biologically independent experiments

By replenish glutathione (GSH), scavenging ROS, or enhancing endogenous antioxidant enzymes, these agents can interrupt the lipid peroxidation cascade and protect AECs from ferroptotic death

A similar K m value of 0.25 mM was reported by Garca-Canovas and co-workers for Agaricus bisporus tyrosinase 26