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SIRT is an intra-arterial brachytherapy primarily used to treat hepatocarcinoma and hepatic metastases, however its use in ICC is not as widespread3,4

10.1126/science.aad4017 144 TongH.JiangZ.SongL.TanK.YinX.HeC.et al (2024)

But the combination of sorafenib and RSL3 significantly inhibited GSTZ1-deficient cell viability and promoted ferroptosis and increased ectopic iron and lipid peroxides in vitro and in vivo (Wang Q