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The resulting acetoxyarylamines are highly unstable, spontaneously forming arylnitrenium ions that bind to DNA (Bland & Kadlubar, 1985) and ultimately lead to mutagenesis and carcinogenesis (Kerdar et al., 1993)

Hypertriglyceridemia, and indirectly insulin resistance, is related to changes in HDL composition and metabolism, leading to an increased clearance of HDL from the circulation

This reduction of total protein amounts can be achieved with RNA interference (RNAi), using gene-silencing mechanisms to target -syn mRNA levels

We thank members of the Li laboratory for their helpful discussion and technical support

Assuming all glutathione tablets work the same