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Thioredoxin ( n =41), TxNIP ( n =39), GST ( n =43) and MnSOD ( n =20) all showed significant increases in expression levels after anthracycline-based chemotherapy ( P =0.00000002, P =0.006, P =0.023 and P =0.048, respectively) (Figure 5)

In response to oxidative stress, gene expression in S