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The cobalt found in the plant tissues is used by rumen bacteria to produce cobalamin (vitamin B12)

A few commenters requested greater transparency around the reopening request process including on the type of information CMS will request, potential timelines, and steps ACOs should take to request reopening, and several of these commenters urged CMS to publish related information in subregulatory guidance

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[5] In summary, NAD+ Injection provides additional coenzyme substrate that may broadly support the cells energy-producing and regulatory enzymes, but its exact biological effects in people remain an area of active research and may vary depending on individual physiology