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We used the Human Protein Atlas and GEO database to observe NRF2 expression in various organ tissues, including skin, and found decreased NFE2L2 expression in psoriatic lesions (Fig

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Since our data suggest that the urea cycle in AKI is already overloaded, it is uncertain what levels of protein intake are necessary to meet metabolic needs and at what point a high protein intake will overwhelm the urea cycle and ammoniagenesis

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