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Lysosomal K+ channel TMEM175 promotes apoptosis and aggravates symptoms of Parkinsons disease

Metabolic profiling, as an "overall model", has high specificity and can distinguish patient populations from healthy populations with considerable accuracy

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Here, we delved into the pathological effects and mechanisms of SCFAs, endotoxins, indole, choline, and endogenous ethanol on the liver (Figure 4)

Other secondary causes of cognitive impairment, including genetic disorders (e.g., Wilsons disease), autoimmune conditions (e.g., SLE), chronic epileptic syndromes, repetitive head trauma (e.g., chronic traumatic encephalopathy) [501], and neoplastic processes or their treatments (e.g., chemotherapy-related cognitive impairment or brain fog) [502], are similarly well defined