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This science-backed approach focuses cold therapy on a specific area of the body knees, back, shoulders, or wherever pain and inflammation hit hardest

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Cell vitality measurements (WST1 assays) of primary (a, c) endothelial cells or (b, d) astrocytes after exposure to vehicle (0, white) or to increasing concentrations of cuprizone (50500 M, red) for 24 h (a, b) or with 250 M cuprizone for 72 h (c, d) ( N = 5 per condition)