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It reduces insulin resistance, inflammation, and oxidative stress while protecting against age-related diseases like cancer and cardiovascular issues

Furthermore, the ablation of GPX4 in neutrophils exacerbates the development of autoimmune diseases, such as systemic lupus erythematosus, by inducing ferroptosis [39]

Clinically, mitochondrial dysfunction symptoms include: dysautonomia (orthostasis, heat intolerance, POTS-like symptoms) muscle rigidity or tremors variable energy levels cognitive fog heightened reactivity to stress worsening symptoms during infection or inflammation poor exercise tolerance These same patterns appear in Parkinsons disease, neurodegenerative disorders, dysautonomia, and trauma-linked hyperarousal