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The data that support the findings of this study are available in the Materials and Methods, Results, and/or Supplemental Material of this article

Methods Antibodies and chemical reagents The following antibodies were used in this study: Annexin V FITC-conjugated (Molecular Probes), mouse fibroblast specific protein-1 (Abcam), mouse CD31 PE-conjugated (Militenyi), mouse CD14 PerCP Cy5.5-labelled (BD Biosciences), mouse B220 PE-Cy5-labelled (BD Biosciences), and human CD44 APC-conjugated (Militenyi) antibodies

Instead of offering immediate volume, it targets skin tightening by stimulating collagen and elastin production over time

Down-regulation of EPAS1 transcription and genetic adaptation of Tibetans to high-altitude hypoxia

However, the clinical use of these drugs is not without challenges, including the development of resistance and adverse effects, such as hypertension and proteinuria, which necessitate careful patient monitoring and management (50, 51)