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These findings highlight the critical role of BRCA mutation status and HRD as predictive biomarkers for PARP inhibitor efficacy and reinforce the need for biomarker-guided treatment selection

The quantity and quality of the extracted DNA were assessed using a NanoDrop ND-1000 spectrophotometer (Thermo Fisher Scientific, Waltham, MA, USA)

Persch TSP, Silva PR, dos Santos SHD, de Freitas BS, Oliveira GT (2018) Changes in intermediate metabolism and oxidative balance parameters in sexually matured three-barbeled catfishes exposed to herbicides from rice crops (Roundup, Primoleo and Facet)

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doi: 10.3390/pr12102223 191 PettinatoE.BhnertP.BergI