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Por su contenido de Vitamina B6 (Piridoxina), se han reportado neuropata perifrica con administracin prolongada, a dosis altas disturbios gastrointestinales, deficiencia de cido flico, sedacin, hipotensin y reacciones drmicas." Embarazo y Lactancia: "Estudios en animales y mujeres embarazadas no han demostrado efecto nocivo para la madre ni el producto

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Its mechanism of action centers on activation of the Innate Repair Receptor (IRR), which helps regulate anti-inflammatory and tissue-protective pathways without producing erythropoietic effects

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Severe GI reactions (peptic ulcer, GI bleeding, and GI perforation) occurred in 0.4% to 4.6% of patients without a history of a peptic ulcer or bleed and in 2.1% to 15.4% of patients with a history of a peptic ulcer or bleed