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(2004) used a transgenic mouse model expressing the autophagosomal marker green fluorescent protein-microtubule associated protein 1 light chain 3 (GFP-LC3) to demonstrate that autophagy is significantly upregulated upon starvation in liver tissue but not in the brain

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One of the most important risk factors for glaucoma is elevated intraocular pressure (IOP), which promotes mechanical stress in RGCs and the lamina cribrosa, blockading axonal transport and causing axonal degeneration 3,4

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