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Think of it as a metabolic support crew

10.1038/s41591-020-0945-x 158 TalbertE

In a randomized placebo-controlled phase II trial in patients with metastatic colorectal cancer, calmangafodipir at a dose of 5 mol/kg reduced oxaliplatin-induced delay in the onset and intensity of CIPN symptoms during and after treatment and had no negative impact on progression free survival and overall survival outcomes [155]