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While human clinical trials are limited, case studies from sports medicine clinics report significant improvements in shoulder pain and function within 4-6 weeks of treatment (Rodriguez et al., 2023)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 83.Nicholas L.M., Morrison J.L., Rattanatray L., Zhang S., Ozanne S.E., McMillen I.C

Any weight loss benefits discussed are based on clinical observations and may not reflect individual outcomes

We interpreted these results as being indicative of profound excitotoxicity in dentate gyrus neurons after chronic exposure to stress hormones to a degree that produces depression-like behavior (Romay-Tallon et al., 2010, 2015)