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Any disruption to this barrier, whether due to infection, uncontrolled inflammation or medical interventions, must be rapidly addressed to mitigate the hosts exposure to harmful luminal contents that would otherwise remain contained

Avoid contact with the eyes, mouth, and other mucous membranes

Okay so I've gone deep really deep and here are the three takeaways

Its efficiency in ubiquitination, LC3-II-mediated encapsulation, and the timing of autophagosome-lysosome fusion collectively determine the rate of mitochondrial clearance [103]

The method of microbial fermentation can promote the full release of the active ingredients in medicinal and edible homologous plants [88,89] and generate new bioactive components