glutathione binding drugs

glutathione binding drugs transferases as mediators of signaling pathways involved in cell proliferation and cell death Glutaredoxin catalysis requires two distinct

Name: glutathione binding drugs transferases as mediators of signaling pathways involved in cell proliferation and cell death Glutaredoxin catalysis requires two distinct
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Glutaredoxin catalysis requires two distinct glutathione interaction sites Nature Communications Glutathione Mediated Conjugation of Anticancer Drugs: An Overview of Reaction Mechanisms and Biological Significance for Drug Detoxification and Bioactivation PMC Full Article Glutathione responsive nano vehicles as a promising platform for targeted intracellular drug and gene delivery ScienceDirect Glutathione Mediated Conjugation of Anticancer Drugs Encyclopedia MDPI

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Description

Miodownik et al., 2019

Lysates were derived from flow cytometry sorted HEK293T cells expressing EMC3mScarlet3HA (EMC3-tag), OST4-mScarlet3HA (OST4-tag) or SEC63-mScarlet3HA (SEC63-tag)

Co-immunoprecipitation studies demonstrated that the peptide reduces eNOS/caveolin-1 binding by approximately 50%, effectively doubling the available eNOS for nitric oxide production

Proper peptide storage maintains potency

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