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PI3KAKTmTOR Consistent with their role in apoptosis suppression, cell proliferation, metabolism and anabolic reactions, the interconnected PI3KAKT and mTOR pathways are hyperactivated in almost 40% of all human cancers

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There is another group of SNOs called high-molecular mass (HMM) SNOs which are produced by NO binding to sulfhydryl (-SH) groups present in specific cysteine residues of proteins