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Furthermore, research indicates that GHK might also influence the activities of metalloproteinases enzymes that initiate extracellular matrix protein breakdown and antiprotease actions

Astrocyte-specific loss of CLEC16A exacerbates neuroinflammation and demyelination in an MS mouse model and corresponds with mitophagic deficits in human MS plaques, highlighting CLEC16A as a novel therapeutic target [245]