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Focusing on the use of chemical tools that target ferroptosis in preclinical studies, we also summarize recent advances in targeting ferroptosis across the growing spectrum of ferroptosis-associated pathogenic conditions

Potential Benefits & Side Effects Observations from clinical literature

Skin dullness

Beyond these established mechanisms, emerging, yet still limited, evidence suggests that glycine may also produce depolarizing effects via glycine-activated excitatory receptors (eGlyRs), including GluN1/GluN3-containing NMDA receptor assemblies that can be activated by glycine in a glutamate-independent manner

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