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MARCH was a 26-week, randomized, placebo-controlled (PBO), Phase 3 trial of maralixibat (MRX), an ileal bile acid transporter (IBAT) inhibitor, that achieved its primary and key secondary endpoints of pruritus and sBA reduction for individuals across the broadest range of PFIC types studied

The initial findings were so impressive that some researchers suggested BPC-157 could be the prototype of a new class of organoprotective agents. There were still many unanswered questions, though: Would other studies replicate these findings

Pesquisas cientficas vm investigando h dcadas os possveis efeitos da molcula sobre cicatrizao, reparo tecidual, inflamao e envelhecimento da pele

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Relative to oral routes, this technique can support comparatively higher systemic availability, faster time to effect, and more consistent dose outcomes