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Following the exclusion of duplicates, a total of 653 articles were selected based on their title and abstracts to determine their eligibility

This cell death mechanism is now receiving widespread attention, extending well beyond its original identification in cancer research, including in the field of drug-induced liver injury

The function of this complex is poorly understood, and the biochemical determinants responsible for its association are unclear, given that importin binds Ran-GDP weakly (Kd ~2 M), and RanBP1 exhibits undetectable binding to Ran-GDP but interacts strongly with Ran-GTP 57