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10.1080/21678421.2018.1536152 88 Dejesus-HernandezM.MackenzieI

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Effect of mechanical loading on insulin-like growth factor-I gene expression in rat tibia

Animal studies have shown that the BCL-2 family inhibitors ABT263 (Navitoclax) and ABT737 effectively eliminate SA--Gal-positive senescent cells, significantly enhancing the function of multiple systems and tissues, such as the haematopoietic and pulmonary systems, as well as skeletal muscle tissue [192, 212]