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Because studies have found that certain plant growth regulators, such as paclobutrazol, can increase the apoptosis rate of liver cells and inhibit the proliferation of photoreceptor cells in the retina [139, 140]

Additionally, viral infections such as Epstein-Barr virus activating IDO may convert tryptophan to kynurenine, supporting this hypothesis [63,64,65,66]

The active form of vitamin D is capable of crossing the bloodbrain barrier, suggesting that vitamin D may have a direct or indirect role in brain and cognitive functions, as reported by Akpinar and Karadag (2022) [28]

Food Funct (2019) 10(6):371726