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Pregnant or breastfeeding women should consult a healthcare professional before use

Issues raised in academic and consumer reviews include irritation in cosmetic-formulation use, very wide variation in product quality across the unregulated marketplace, formulation-stability problems, ingredient-interaction concerns, and a thin clinical-trial evidence base relative to the strength of consumer marketing claims

The peptide also increases elastin production by 30% and dramatically upregulates decorin, a proteoglycan that regulates collagen organization

While many medications aimed at treating chronic inflammatory disorders suppress the immune system, KPV is thought to regulate inflammation while maintaining normal immune function

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