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Researchers reported that MOTS-c administration significantly enhanced physical performance in mice across various ages, improving exercise tolerance in not just young but also middle-aged and old mice

It is believed that excessive amounts of ROS can cause genomic instability [11], leading to a variety of chronic diseases, including atherosclerosis, arthritis, diabetes, alzheimers disease, neurodegenerative diseases, and cardiovascular diseases [12,13,14,15,16]

Vermes A, Guchelaar HJ, Dankert J

Figure 4 shows the integrated network of cell death pathways triggered by Erastin in endometriosis, illustrating how ferroptosis, necroptosis, and pyroptosis are interconnected and modulated by autophagy-dependent processes