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This model proposes an overall dumbbell shape similar to that reported for mammalian MTs (Bilecen et al., Fucus vesiculosus MTs (Merrifield et al., 2006)

Somatic Miwi2 modulates mitochondrial function in airway multiciliated cells and exacerbates influenza pathogenesis

This means that if you activate the enzyme (raising its Vmax), the Hcy concentration will drop so the flux through CBS remains the same at steady state

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