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doi: 10.1080/09513590.2019.1648413 81 DolmansMMDonnezJ

Existing data primarily comprises: Animal Studies: While promising preclinical results exist, the extrapolation of these findings to the human context is limited by inherent interspecies differences in physiology and metabolism

This is a signal-discovery instrument: proportions are among side-effect-disclosing posters rather than population rates, and symptom posts are structurally under-represented against progress posts, so it supports vocabulary and theme prominence, not magnitude

"Velcade (Bortezomib) Receives 2 New FDA Indications: For Retreatment of Patients with Multiple Myeloma and for First-Line Treatment of Patients with Mantle-Cell Lymphoma"