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Typically, organic chemists compare the various values from their determination in water, DMSO and the gas phase and use these to predict a compounds reactivity, solubility, and other physical characteristics

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Reductive N - methylation Although we did not detect direct evidence for reactions between HCHO and unmodified AA N -amino groups under standard conditions, such reactions likely occur (given the nucleophilicity of amino groups) and are potential intermediate steps in the formation of cyclic products

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