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Description

Imtiaz et al

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Dual role of AMPK in mitochondrial dysfunction and metabolic reprogramming in PH According to research, reduced AMPK function in PPHN led to mitochondrial dysfunction and impaired angiogenesis, suggesting a critical interplay between AMPK, mitochondria, and vascular development in PPHN

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importantly, suppressing this axis reduced metastatic fitness, supporting FSP1 as a context-selective vulnerability in melanoma progression 117

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