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After initial treatment with antibiotics and thiopurines, which are useful adjunctive treatments despite their limited and unproven efficacy when used alone, biologic therapies are often used as the next option

Building on this adaptability, Hammouri and colleagues [636] introduced the Neyman Weighted Multiple Testing Procedure, which incorporates stage-specific weighting, dynamic sample redistribution, and sequential testing to enhance decision-making while rigorously controlling type I error rate

Magalhaes R, Almeida G, Ferreira V, Santos I, Silva J, Mendes MM, et al

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Clinical Studies Several clinical trials have examined the effects of glutathione on kidney health