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Glial Cells Associated with Ferroptosis After Ischemic Stroke Iron Overload-Induced Ferroptosis of Glial Cells After Ischemic Stroke Microglia exhibit significantly higher iron levels than neurons, playing an important role in regulating iron homeostasis after cerebral ischemia (Bishop et al

The experimental group received oral liposomal glutathione (L-GSH) for three months and while the placebo group received the oral empty liposomes for three months

Similarly, in Nrf2-KO mice, there are higher levels of proinflammatory genes such as IL-1, IL-6, IL-8, iNOS , and COX-2 , and a decrease in the expression of antioxidant enzymes like hemeoxygenase-1 and GST Mu-1 (93)

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