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Patients, investigators, and all of the personnel involved in the study were blinded to treatment allocation whereas information regarding previous statin therapy and simvastatin dose during the run-in and the study treatment periods remained unmasked

4 DPN affects approximately 50% of individuals with diabetes during their lifetime and can be classified based on the type of nerve fibers affected

Patients underwent median nerve conduction study and were administered the Boston Carpal Tunnel Syndrome Questionnaire (BCTQ) and Neuropathic Pain Symptom Inventory (NPSI) questionnaire

Adult migraine patients have elevated blood levels of TNF-, IL-1, IL-6, IL-18, and IL-10 during migraine episodes (Dnder et al., 2021

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