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Disclosure of interest: None E-Posters - ACUTE ISCHEMIC STROKE MANAGEMENT 01.00 - ACUTE ISCHEMIC STROKE MANAGEMENT - 01.02 - ACUTE MANAGEMENT - Thrombolysis or thrombectomy P2145 - ESOC25-2493 REDUCING DOOR-TO-NEEDLE TIMES IN ACUTE ISCHEMIC STROKE IN A PUBLIC HOSPITAL IN COSTA RICA Juan-David Riveros 1 , Barrantes-Silman Paula 1 , Perez-Andrade Isamar 1 , Barboza Miguel A

Oxidative inactivation of thioredoxin as a cellular growth factor and protection by a Cys73 Ser mutation

10.1016/j.cois.2018.04.007 13

These antioxidant effects reduce the risk of developing various chronic diseases and neurodegenerative disorders

Interestingly, no tolerance for locomotor effects or anxiolysis appears in ARM-390-treated animals underlying the fact that biased agonist could be used at the behavioral level