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The newly discovered DNA methylation patterns were then individually amplified using allele-specific PCR in order to be further analyzed in a more detailed matter [57]

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Recently, QE/anti-PD-1 antibody combination therapy reshaped HCC tumor microenvironment in mice in parallel with regulating the gut microbiota and macrophage immunity, suggesting that traditional Chinese medicine ingredients in combination with PD-1 inhibitors could be a potential new strategy for HCC treatment (Wu et al., 2023)