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Once activated, the SMAD family member 4 (SMAD4) enters the nuclei and regulates the expression of genes inhibiting myoblast proliferation and differentiation, such as paired Box 3 (Pax3) and MyoD [120]

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doi: 10.3389/fgene.2020.00095 Received 05 November 2019 Accepted 28 January 2020 Published 28 February 2020 Volume 11 - 2020 Edited by Nejat Dalay, Istanbul University, Turkey Reviewed by Girdhari Lal, National Centre for Cell Science, India

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More importantly, as a natural chemical molecule, the targets of TMAO in vivo are not fully elucidated

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A new GLS1 inhibitor compound 27 (IPN60090) was developed by replacing the flexible core of CB-839 with heterocycles

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