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Das erfindungsgeme Mittel kann zustzlich Proteinhydrolysate umfassen, vorzugsweise kationisierte Proteinhydrolysate, wobei das zugrunde liegende Proteinhydrolysat vom Tier, beispielsweise aus Collagen, Milch oder Keratin, von der Pflanze, beispielsweise aus Weizen, Mais, Reis, Kartoffeln, Soja oder Mandeln, von marinen Lebensformen, beispielsweise aus Fischcollagen oder Algen, oder biotechnologisch gewonnenen Proteinhydrolysaten, stammen kann

FIGURE 1 2 Trimethylamine N-oxide and chronic kidney disease 2.1 Trimethylamine N-oxide is a risk factor for chronic kidney disease Risk factors for chronic kidney disease are various, including disease factors (Diabetes, hypertension, autoimmune diseases, systemic infections, urinary tract infections, acute kidney injury, etc.), Sociodemographic factors (age, gender, ethnicity, and family history of CKD, etc.), and lifestyle factor (smoking, heavy alcohol use, obesity, etc.) (Taal and Brenner, 2008

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159 The notable abnormalities in host metabolism diminish nutrient and oxygen availability within the TME and lead to the accumulation of metabolic byproducts, which undoubtedly pose additional threats to cellular health and function