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8, 201209, doi: 10.1111/1758-2229.12369 (2016)

The Energy and Protection Loop When your mitochondria produce energy (ATP), they naturally create by-products called reactive oxygen species (ROS)

J Biol Chem 278:85168525

By forming a ternary complex between the protein of interest and E3 ligase, PROTACs facilitate ubiquitination and subsequent degradation of target proteins [222]