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Synthesis of (((ethane-1,2-diylbis(azanediyl))bis(carbonyl))bis(4,1-phenylene))diboronic acid(EBPBA) 4-Carboxyphenylboronic acid (3.65 g, 22.00 mmol), ethylenediamine dihydrochloride (1.33 g, 10.00 mmol), HATU (11.40 g, 30.00 mmol) and HOAT (4.08 g, 30.00 mmol) were dissolved in DMF (40 mL) under nitrogen atmosphere and ice bath conditions

Results: 591 patients were screened and 162 were randomized

Latchoumycandane et al

It demonstrates considerable cytotoxicity, stimulates p53 expression, elevates ROS generation and lipid peroxidation, while simultaneously reducing SLC7A11 and GPX4 levels

Therefore, measurement of the cellular GSH level has been used to evaluate the severity of oxidative stress and redox buffering capacity [12]